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used optogenetics to study excitatory projection neurons and inhibitory PV neurons of the mPFC and subsequently found that an increase in the cellular E/I ratio leads to severe impairments in information processing and behaviour

Kosho T, Miyake N, Hatamochi A, Takahashi J, Kato H, Miyahara T, Igawa Y, Yasui H, Ishida T, Ono K, Kosuda T, Inoue A, Kohyama M, Hattori T, Ohashi H, Nishimura G, Kawamura R, Wakui K, Fukushima Y, Matsumoto N

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The BPC-157 monograph, for example, reads partly like a reference sheet for practitioners, including common uses, suggested doses, and IPS Level of Evidence labeling, not just a neutral evidence synthesis

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