39 ImaiH.HiraoF.SakamotoT.SekineK.MizukuraY.SaitoM.et al (2003)
It significantly reduces serum levels of follicle-stimulating hormone (FSH) and luteinizing hormone (LH), which are key gonadotropins that promote estrogen-dependent lesion growth, while also lowering pro-inflammatory interleukin-6 (IL-6) and the lipid peroxidation marker malondialdehyde (MDA)
In a clinical or home-care setting, this kind of reliability is definitely a big deal
Dosage depends on product form, intended use, clinical context, and individual health factors
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The science backs this up