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Furthermore, IFN-induced arginine depletion, subsequent GCN2 expression, and autophagy contribute to the transformation of bovine epithelial mammary cells and tumorigenesis [94]

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Although these dermatological changes are not life-threatening, they frequently contribute to significant psychosocial distress and have been associated with systemic inflammatory activation (70)

Recent studies, however, have broadened our understanding, revealing their potential roles in producing persulfides and polysulfides ( 2 S is converted to thiosulfate and sulfate (Libiad et al., 2014