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[DOI] [PMC free article] [PubMed] [Google Scholar] Levy EJ, Anderson ME, et al

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Observational studies have noted that individuals with gallstones have lower blood levels of alpha-tocopherol and alpha-tocopherol/cholesterol ratios, and lower dietary intake of alpha-tocopherol, as compared with unaffected individuals (Waniek 2018

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Excessive cleavage of mature LRP-1 by the enzyme Furin could be the cause of increased LRP-1-ICD levels [273, 274]