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LOH reportedly affects 7-30% of aged males [4] and may be a significant detriment to their quality of life, adversely affecting the function of multiple organ systems [5]

The mitophagy pathway and its implications in human diseases

However, many individualsparticularly those with autism spectrum disorder (ASD), epilepsy, schizophrenia, and Parkinsons diseaseexperience low folate levels in the brain despite normal blood folate levels

While GHK-Cu delivers copper in a chelated form that prevents oxidative damage, extended continuous use could theoretically affect copper homeostasis

Based on the mitochondrial toxicity in cancer cells, ASA may also be classified as a potential mitocan

J Biol Chem 274(17):1145511458