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68 A systematic, evidence-based review 9 concluded that corticosteroid injections appear to be relatively safe and seem to have a short-term effect (two to six weeks)

Pollard et al

Treadmill exercise reduces neuroinflammation, glial cell activation and improves synaptic transmission in the prefrontal cortex in 3 x tg-AD mice

Electrophysiology Neurons were constantly perfused at 3 ml min 1 with heated (3032 C), gassed (95% O 2 , 5% CO 2 ) artificial cerebrospinal fluid (pH 7.4, 300305 mOsm) containing (in mM): 119 NaCl, 2.5 KCl, 1.3 MgCl 2 , 2.5 CaCl 2 , 26 NaHCO 3 , 1.3 NaH 2 PO 4 , 20 D-glucose and 0.5 sodium ascorbate

A typical U.S

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