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Chronic tolerance to nicotine in humans and its relationship to tobacco dependence

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THE TOBACCO LEAF January 9, 1954 Contention that Tobacco Causes Disease Does Not Agree with Authentic Biological Conceptions (4 pages) Column by James Coughlin, MD, FACS THE TOBACCO LEAF March 13, 1954 For thousands of years, primitive and aboriginal people used tobacco in different ways without harmful effects, but modern man has been and is trying to prove the plant is harmful and disease forming

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The self-medication hypothesis proposes that people with schizophrenia experience an improvement in symptoms of psychosis and in the side-effects of antipsychotic medication following smoking

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