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On the contrary, administration of dynasore (inhibitor of VEGGR2) didnt activate the pathway and blocked endothelial tube formation [3]

In the pig LR3 IGF-1 study, plasma endogenous IGF-1 was suppressed during infusion (Tomas et al., 1997), and the guinea pig study showed reduced plasma IGF-I and IGF-II during LR3 administration (Bastian et al., 1995)

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Research continues to focus on peptides and their potential applications

Integrating these novel approaches with traditional therapies to create a multifaceted treatment strategy that addresses the complexities of GBM seems crucial

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