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Consistent with these mechanisms being physiologically relevant, e-cigarette users have been shown to have increased levels of systemic biomarkers of oxidative stress 65 and inflammation (e.g., IL-1, IL-6, IL-8, IL-13, IFN-, and MMP-9) 66 , and increased levels of metals and metallothioneins in the urine 67

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The UK government has committed to achieving a smoke-free generation by 2030, defining that target as reducing adult smoking prevalence to below five percent

We also pooled these effect sizes to obtain non-specific global risk estimates

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Incapsula incident ID: 1849000641029720406-1267952690398826556