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You should have little resistance to the injection and skin should not bubble up during injection

In both groups, a large majority of patients received a PD-1 or PD-L1 inhibitor, and only a few patients received a CTLA-4 inhibitor or immune checkpoint inhibitor combination therapy

Current therapeutic strategies exploring NAMPT inhibitors in combination with drugs such as lactate dehydrogenase inhibitors and cisplatin have shown efficacy in reducing growth of lymphoma and cholangiocarcinoma 45,46

TMT, Trail Making Test WAIS, Wechsler Adult Intelligence ScaleRevised

Acknowledgements The authors gratefully acknowledge Fadwa Shokry Elbaz for her expertise in designing and illustrating the figures presented in this manuscript

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