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Pharmacokinetics and Oral Bioavailability The original mouse studies used administration routes intended to establish biological proof of concept

Glutathione synthesis could be affected by fast CBS, in effect flooding and overwhelming GSS, or a GSS SNP could directly reduce its activity

Yoshino et al., 2018)

doi: 10.1016/j.alit.2016.06.001

Regulation of transcription of the glutathione S-transferase P1 gene by methylation of the minimal promoter in human leukemia cells

BPC-157 works locally at the site of injury to stimulate repair, while TB-500 works systemically to enhance cell mobility , boost recovery from the inside out, and accelerate healing across multiple tissues