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Subsequently, assessment of characteristic extrahepatic manifestationssuch as KayserFleischer rings, neurological symptoms, and Coombs-negative hemolytic anemiais essential
However, it is important to note that the vast majority of this data comes from animal models, and human clinical trial data remains limited
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GSH in fact is both a nucleophile and a reductant, and therefore can react with electrophilic or oxidizing species rendering the former molecules more soluble and excretable, and the latter unable to interact with more critical cellular constituents such as lipids, nucleic acids and proteins