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Rights and permissions About this article Cite this article Lucero, M.Y., Chan, J

Until the 1980s, when its antioxidant action was discovered, bilirubin was thought to be a harmful by-product linked with the potentially fatal disorders of neonatal hyperbilirubinemias, acute hepatitis, and cirrhosis

Additionally, NRF2 also regulates the expression of the solute carrier family 7 member 11 (SLC7A11), which encodes the cystine/glutamate transporter XCT [23]