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Localized scalp injection theoretically increases dermal concentration at the follicle site, but it also limits systemic distribution that might benefit follicles across the entire scalp
Hence, it's best to avoid such contact for a few hours following the injection
For severe cases, the first dose is usually 1,000 mcg given intramuscularly every day or every other day for a week or two
Interaction with fasting and ketosis Both fasting and ketogenic diets increase NAD+ levels through various mechanisms
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Since pS10-H3 is a marker for chromosome condensation linked to mitosis, cellular stress (51) and DNA damage (52), its elevation in the triple drug combination likely reflects both a proliferation block and a stress response to vincristine
