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Preclinical fat-loss evidence Ng et al
Keep simple logs of injection timing, sites, doses, and any effects noticed
The combination of the restrictive diet and increased physical activity is also what makes weight loss so difficult as the more you work out, the more your appetite is likely to increase, and the more nutrients you will require in order to ensure that your body is getting all of the nutrients it requires in order to keep exercising and burning the stored fat
The most common reports are mild stimulant-like effects (warmth, slightly higher resting heart rate), insomnia if dosed late in the day, and mild stomach upset with capsules
However, the largest Phase IIb trial involving 536 participants failed to demonstrate statistically significant weight loss compared to placebo at the primary 12-week endpoint, leading to development termination in 2007
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