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The study aimed to compare the effects of intermittent fasting with a traditional low-calorie diet on various health parameters, including liver health as assessed by fibro scan and biochemical evaluations

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Kalita, J., S

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Phase I pilot (three healthy male volunteers, subcutaneous administration, 1996, PMID 8637402), increased facial, upper-body, and buttock pigmentation persisting approximately one week after cessation of dosing was reported alongside nausea and somnolence

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BH4 treatment resulted in an increase in methionine but this increase was only borderline significant [ F (1, 26) = 3.91, p = 0.06

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10.1002/hep.30762 65

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