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Discussion In this paper we sought to examine the relationship between vitamin B 12 deficiency and glutathione (GSH) levels in diabetes from a theoretical standpoint

This supports a model in which CHAC1-mediated GSH depletion destabilizes NRF2 and reduces cystine import, allowing iron-dependent lipid peroxides to accumulate and trigger ferroptosis

Thiol-specific fluorogenic agent for live cell non-protein thiol imaging in lysosomes

2 B, D, F )

A 2025 case report documented severe fever, abrupt liver damage, and clotting problems associated with high-dose IV glutathione, which is uncontrolled

Redox modulation of endothelial nitric oxide synthase by glutaredoxin-1 through reversible oxidative post-translational modification