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Reasonable candidates are adults seeking specific outcomes (recovery support, longevity optimization, aesthetic improvements) with appropriate baseline health who are willing to engage seriously with medical evaluation and ongoing follow-up

Additionally, studies have detected a significant reduction in neuronal density in the hippocampus and a prominent decrease in neuronal size in the ACC of bipolar subjects relative to controls (166, 167)

A massive 2024/2025 observational study published in PNAS (MedRxiv preprint) analyzed data from over 3,925 patients suffering from Long COVID and ME/CFS

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