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For individuals with pernicious anaemia or a condition that prevents B12 absorption, injections are medically necessary because oral supplementation will not be absorbed effectively

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B12 offers benefits such as: reduced risk of heart disease reduced risk of stroke reduced risk of vision loss supporting neurological function healthy cell growth, repair, and reproduction mood regulation healthy digestion A person who eats meat, fish, or dairy usually gets enough B12 from their diet

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Modules correlated with the KO genotype were enriched for neuronal and synaptic genes involved in vesicle-mediated transport, neurotransmitter secretion, and GTPase activity, suggesting that RAMP deletion disrupts synaptic signaling networks critical for metabolic regulation [2]

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