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Its one of the most effective drugs for quitting smoking, but its also been linked to psychiatric side effects like depression, paranoia, erratic behavior, and even suicidality, which led to the FDA adding a black box warning

Thirdhand aerosol is the mixture of chemicals in e-cigarette/vape pen aerosol that remain on surfaces and in dust, even after the aerosol is gone, and react with other chemicals in the environment to form toxic chemicals

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Carmella et al