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Depression comorbidity in migraine

Abnormal ROS signalling in OA synovial fibroblasts induced by cytokines, thrombin or stress is related to the increased activity of nuclear factor erythroid 2 p45-related Factor 2 (NFE2L2, also known as NRF2) (Bernard et al., 2017)

Key Terms Explained GHK-Cu (Glycyl-Histidyl-Lysine Copper) A naturally occurring tripeptide (three amino acids: glycine, histidine, lysine) bound to a copper ion

Lesions can be induced by a variety of stimuli including standing, walking, wearing tight clothes or sitting on a hard surface