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These findings provide a robust methodological platform for tobacco research as well as mechanistic insights into how prolonged smoke exposure promotes epithelial adaptation, revealing NRF2-dependent resilience as a crucial early marker in smoking-related lung cancer development
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It acknowledges that tackling this inequality is the core challenge in the years ahead and that if England is to achieve being a smokefree society by 2030, bold action is required to both discourage people from starting in the first place and support smokers to quit
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