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The intracellular environment in macrophages has been strongly associated with the induction of metabolic indolence and antibiotic tolerance 7,8,9,10,11

While the results are promising, a lot of evidence is anecdotal or from animal studies

It depends on the context of the research

The studies specifically looking at soft tissue healing also spread the assessment of healing markers throughout the research period, involving data collection at various time points, for example, 1, 4, 7, 10 and 14 days throughout a 14-day study

The cancelled 2015 Phase I trial (NCT02637284) was almost certainly abandoned for this reason rather than buried by a regulator