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Dihexa (PNB-0408) (2-4mg/kg;b.wt.;16 weeks) is promising candidates for adjunct therapies to promote limb functional recovery after surgical nerve repair, and have implications in peripheral nerve injury and limb transplantation [8]
Wiegman CH, Michaeloudes C, Haji G, et al
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Preliminary findings from these studies suggest a tolerable oral dosage of approximately 100mg/kg in mice [1]
The role of reactive oxygen species and ferroptosis in heme-mediated activation of human platelets