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To ensure these effects were not cell-line specific, we investigated the impact of J8 and J10 in two other lung cancer cell lines with elevated DDX3X expression, NCI-H460 and NCI-H1975, obtaining similar results (Fig

There are numerous risk factors for -cell failure

Strohm et al., 1995

Selective FLT3 Inhibitor FI-700 Neutralizes Mcl-1 and Enhances p53-Mediated Apoptosis in Acute Myeloid Leukemia (AML) Cells with Activating Mutations of FLT3-Via Mcl-1/Noxa Axis

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PMID: 24384493