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In a murine intratracheal inoculation model, TMV was detected within lung tissue and localized in the cytoplasm of alveolar macrophages, persisting for up to 14 days despite the absence of productive replication ( These findings indicate that TMV is not merely an environmental contaminant but can access the respiratory microenvironment in vertebrate hosts

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Nicotine modulates molecules of the innate immune response in epithelial cells and macrophages during infection with M

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