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confirmation with medical imaging is usually required

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Baseline questionnaire data include information on key demographic and health-related factors, including Indigenous status, country of birth, household income, level of education, smoking, alcohol use, physical activity, height and weight and medical and surgical history

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Two key genetic factors are: APOE (Apolipoprotein E) : Variants of this gene, like APOE4 , are linked to higher LDL-cholesterol levels and a greater risk of heart disease, while APOE2 may be associated with lower LDL-cholesterol