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It plays a pivotal role in protecting cells from damage caused by free radicals and oxidative stress, both of which can adversely impact skin health and accelerate the ageing process

(Wallingford, CT: CAB International), 97108

These new endpoints have not been widely validated for skin irritation responses

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So interesting, esp since theyre also going after grandfathered medicines (pre-dating FDA existence)

McGeer EG, McGeer PL