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Reduced secretion of gastric acid and pepsin, from the use of H 2 blocker or proton-pump inhibitor (PPI) drugs, can reduce the absorption of protein-bound (dietary) vitamin B 12 , although not of supplemental vitamin B 12

Taking B12 supplements can be an effective way to treat B12 deficiencies and isnt necessarily inferior to B12 shots

Gwyer D, et al

The injection delivers Vitamin B12 directly into the body without requiring a full IV drip appointment

These are not hypothetical problems

The travel guide for GLP-1 medications covers additional tips for navigating airports with injectable medications, and the same principles apply to compounded tirzepatide