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A case of severe glutathione synthetase deficiency with novel GSS mutations

PLP acts as a cofactor for numerous enzymes involved in amino acid metabolism, particularly those associated with neurotransmitter synthesis, like serotonin, dopamine, and gamma-aminobutyric acid (GABA) (5759)

Kawamoto, Y., Wu, Y., Takahashi, Y

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These injections provide significant relief from pain, numbness, and tingling in the hand and wrist area

doi: 10.1172/JCI74915 85 MaidaAZotaASjbergKASchumacherJSijmonsmaTPPfenningerAet al