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A randomized, placebo-controlled trial in 559 elderly individuals with low serum levels of folate and vitamin B 12 and at increased risk of fracture evaluated the combined supplementation of very high doses of folic acid (5 mg/day) and vitamin B 12 (1.5 mg/day)

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As regulatory requirements become more stringent and consumer expectations for product quality and transparency continue to rise, the competitive advantage favoring larger, better-capitalized manufacturers is expected to intensify, potentially resulting in further consolidation within the industry