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Recognizing the Causes of B12 Deficiency Treating vitamin B12 deficiency requires more than just supplementing with B12

Special Populations with Increased Needs Certain groups face greater risk for low B12 or have higher requirements: Older adults : Reduced gastric acid impairs release from food proteins

Scientific Reports (2021) 5

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Journal of Orthopaedic Research , 24(5), 982989

When You Might Need Higher B12 Doses While the standard RNI of 1.5 mcg per day suffices for most healthy adults, certain medical conditions, dietary patterns, and medications can substantially increase B12 requirements or impair absorption, necessitating higher therapeutic doses under medical supervision