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A deeper mechanistic understanding of how systemic signals modulate ferroptosis-immune crosstalk in vivo may enable the development of therapeutic strategies that precisely recalibrate necroinflammatory pathways, thereby delineating how targeted modulation of necroinflammatory pathways can be leveraged to uncouple cell death from adverse immune effects and thereby refine future therapeutic strategies

The mean follow-up was 5.8 years, with 2,261 deaths (14%) in the PDE5i group and 521 (26%) in the alprostadil group

10.1016/j.fct.2016.07.008 [DOI] [PubMed] [Google Scholar] Pastoriza, S

10.1093/humrep/deaa194 Hum Reprod

Bone Marrow Transplant 14(3):449-53, 1994