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Cross-sectional studies have shown that plasma and tissue glutathione concentrations decrease by approximately 10-15% per decade after age 45, and this decline is accelerated in conditions associated with chronic oxidative stress, including type 2 diabetes, cardiovascular disease, neurodegenerative diseases, HIV/AIDS, chronic liver disease, and chronic obstructive pulmonary disease (COPD) [2][3][10][11]

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10.3389/fpls.2017.00285 Front

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60 Furthermore, clinical studies have found TLK199 to be able to promote the maturation of hematopoietic progenitor cells, induce cancer-cell death, and inhibit myeloproliferative diseases