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Safe Improvised Smoking Devices When conventional options aren't available, some safer improvised solutions include: Apple or other fruit pipes : A hollowed apple creates a natural, disposable pipe Rolling paper alternatives : Clean, unbleached paper (not magazine or colored paper) Empty toilet paper rolls with dryer sheets : For filtering smoke, not as a primary smoking device As explored in this article on creative smoking alternatives, the materials used in DIY solutions significantly impact safety

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APOE genotype, polygenic risk and dementia risk Dementia risk was significantly higher among APOE-4 allele carriers compared to non-4 allele carriers (Supplementary Fig

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When a safer alternative is available, we can reasonably project its long-term risks, when the worlds top medical bodies including the US FDA have approved them, there is no reason to put the lives of millions of Indians at risk