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These molecules also serve normal signaling functions, but excess production can damage lipids, proteins, enzymes and DNA

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Currently, there are clinical studies using AAV vectors to transfect sarcoplasmic/endoplasmic reticulum Ca (2+)-ATPase (SERCA2a) to treat heart failure [255, 256]

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The final model identified higher age, higher NIHSS at index event and pre-stroke disability (defined by mRS) as predictors of poor 6-month outcome