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Large amounts of foam mean peptide is trapped in air-liquid interfaces, reducing the actual concentration of your solution

Tirzepatide is the older, fully matured story: a single-molecule dual incretin agonist taken from discovery through Phase 1 proof-of-concept, [7] then through the large SURPASS (diabetes) and SURMOUNT (obesity) Phase 3 programs, and finally to FDA and EMA approval

doi: 10.1007/BF02087908

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