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Furthermore, in contrast to GSH and Glu, the recently identified Riccas factor TGGs, was shown to rely on both GLR3.6 and GLR3.3 to trigger the systemic defense response 6

Answer: Injected glutathione enters circulation directly and raises the antioxidant supply available inside cells, where it quenches free radicals, binds toxins for elimination, and supports the liver's detoxification machinery