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Shin SY, Fauman EB, Petersen AK, Krumsiek J, Santos R, Huang J, Arnold M, Erte I, Forgetta V, Yang TP et al : An atlas of genetic influences on human blood metabolites

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The most recent meta-analysis on the topic found that current dual use of CCs and ECs was associated with 2040% higher odds of disease, than CC-only smoking 16