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A number of brain regions have been identified as targets of nicotine-induced plasticity, including the mesolimbic reward pathway and the amygdala (Adinoff, 2004)

Elsewhere in the world, the United States and New Zealand, for example, have banned puffs for similar reasons

10.1016/j.earlhumdev.2007.08.002 [DOI] [PubMed] [Google Scholar] 6

For example, in a 10 week longitudinal study, the subjects at first smoked their usual brand followed by different types of research cigarettes with progressively lower nicotine content, each smoked for 1 week

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