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Nicotine dilates blood vessels, leading to increased blood supply in the brain, heart and other vital organs, making the drug addictive and increasing the risk of triggering cardiovascular diseases, said Tejinder Singh, a senior medical oncologist at Apollo Hospital in Navi Mumbai

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Further, nicotine can cause neurotoxicity that damages brain cells

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We also confirmed the endogenous Parkinp53 complex in both immunoprecipitates of endogenous Parkin and p53 prominently in the cytosolic lysate of aged hearts (Fig