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The moist STPs Q1, Q2, MS2, and S2 showed a high abundance of toxin genes whereas Q3, K1, and K2 also contain a significant prevalence of these genes compared to K3, MS1, MS3, and S1 products (Figure 8 and Supplementary Table 6)

Even if the risk of harm to some youth who otherwise would not have smoked is marginally increased, such risks are substantially eclipsed among both youth and adults by the benefit of displacing smoking with safer nicotine products (55)

Their flavor, texture, and even safety can change depending on storage, age, and exposure to environmental factors