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CJC-1295 is a synthetic analogue of growth hormone-releasing hormone that extends the half-life of the GH signal significantly compared to native GHRH

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Laboratory studies demonstrate that ES2 peptides show 3-7 times more potent senolytic activity than FOXO4-DRI in both in vitro and in vivo experimental systems, while CPP-CAND demonstrates approximately 1.2-fold higher selectivity despite shorter peptide length