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a patients were taught to self inject b we could buy injectable B12 OTC This paper from 1983 focuses on pernicious anaemia rather than the many other causes of B12 deficiency, much like today, patients who do not have a definitive diagnosis of PA are considered to be in need of less treatment (or none at all) despite the severity of symptoms being exactly the same

Heffernan MA et al

Secondary DM (E08): Conditions that destroy pancreatic tissue (chronic pancreatitis, cystic fibrosis, hemochromatosis, pancreatic cancer) or cause hormonal insulin antagonism (Cushing syndrome cortisol excess

Thiamine (Vitamin B1) Essential for energy generation, brain and nerve function, and cardiac muscle activity

Lab tests show pp 332 activation leads to suppression of lipogenic gene expression and activation of genes involved in mitochondrial biogenesis

Hung, 2003)