This emphasizes the significant role of vitamin B12 in DNA synthesis, myelin sheath maintenance, and cell metabolism, underscoring its essential contribution to promoting good health
Also, dont forget that B12 and folate need each other to perform
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In mouse models of highfat dietinduced liver steatosis, it significantly inhibits hepatic NNMT activity, reduces NAM methylation, increases NAD+ and SAM levels, enhances mitochondrial fatty acid oxidation, reduces hepatic triglyceride and lipid accumulation, lowers lipotoxicity markers (e.g., malondialdehyde, transaminases), improves hepatocellular injury, and reverses steatosis
They activate different intracellular signaling cascades (cAMP/PKA pathway in fat cells vs incretin signaling in gut and brain)
