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Although IL-18 knockout mice exhibit reduced pulmonary inflammation and emphysema compared to wild-type mice after cigarette smoke [21, 24], pulmonary inflammation occurred independent of NLRP3/caspase-1 axis after four weeks of cigarette smoke exposure [25]

Additional factors that negatively impact root health may enhance systemic insecticide injury, such as leaving treated seedlings in float trays for more than 72 hours after insecticide treatment

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