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E., Elias, C

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Despite progress in tobacco control efforts, smoking remains a global public health concern with diverse patterns observed across countries

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COPD is a heterogeneous condition, with between-individual variation in the nature and severity of airway inflammation [42] and the inflammatory cell profile also varies in large and small airways and with severity of COPD, hence careful appraisal is needed [43]

Buprenorphine has a ceiling effect, which means that a higher dose does not produce increased effects after a certain point