Obstet Gynecol 2006;108:162-168
The safety issues are still the unknown, versus so far the safety looks to be good, right
By inhibiting the NNMT enzyme, it prevents the excessive consumption of NAD+, a critical molecule that your cells need for energy production, DNA repair, and maintaining healthy metabolic function
The cartilage/chondrocyte data supports this
Further, yellow-coloration of glutathione (GSH) in the pancreatic tissue as a marker of antioxidant capacity, was carried out according to the method of Ellman 27 using DTNB (2, 2-dinitro-5,5-dithiodibenzoic acid) that reacts with SH groups to produce a yellow-colored complex which is measured colorimetrically at 412 nm
Bedner, P