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Oxidative stress and the pathogenesis of endometriosis

This content is for educational purposes only and does not constitute medical advice, diagnosis, or treatment

Orre, M

The same was done for the GOSE groups

Aging leads to a loss of CYP19, a key enzyme in estrogen synthesis, resulting in the upregulation of pro-apoptotic genes such as p53 and Bax, thereby promoting granulosa cells apoptosis (Britt et al., 2000