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In addition to catalyzing this major CoQ 10 -reducing reaction, complex I pumps protons into the intermembrane space, generating a proton motive force that drives ATP synthesis 68,70

They showed increased OS status in the testes and epididymides of hypertensive rats as evidenced by a significant reduction in total and non-protein thiol levels, glutathione S-transferase (GST) activity with a concomitant increase in DFCH oxidation and TBARS production

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